Amprolium is a common anticoccidial medication used in the treatment and prevention of coccidiosis
in chickens and turkeys. In the United States, it is one of the few medications approved by the FDA for use in egg laying hens. There is no withdrawal period. Amprolium works by mimicking thiamine (Vitamin B1), which is what cocci require to grow and reproduce inside the chicken. When cocci ingest amprolium, they experience thiamin deficiency and starve from malnutrition. This is why it's important not to administer Vitamin B1 to chickens who are concurrently being treated with amprolium.
: Amprolium has a very narrow margin for error and overdoses can lead to hemorrhagic diathesis and death. Should not be given to chickens concurrently with any B Vitamins.
Chicks on a diet of medicated starter feed should NOT be administered any additional coccidiosis medications. It can result in Thiamine deficiency
Make drinking water fresh daily. Any medicated water which is not consumed within 24 hours should be discarded. Stock solutions for proportioners may be stored in a clean, closed labeled container for up to 3 days. Store between 5°-25°C (41°-77°F) with brief excursions to 40°C. The shelf life of the drug is 5 years from the date of manufacture.