St. John's Wort

Hypericum perforatum

St. John's wort

Other Names:

HPE, Spotted St. John’s Wort, Hypericum, Klamath Weed, Goat Weed, Touch-and-heal, Rosin Rose


  • Antiviral
  • Anti-inflammatory
  • Antitumor
  • Antibacterial
  • Wound-healing
St. John's wort (SJW)(Hypericum perforatum) is a medicinal herb which contains hypericin, the major neuroactive component of the plant. It has been used as a herbal remedy for a number of conditions since the ancient Greeks. Specific applications studied in poultry include:
  • Immune enhancement and Antiviral: St. John's wort extract (HPE) has demonstrated significant therapeutic efficacy and improvement of immunologic functions for chickens infected experimentally with infectious bursal disease virus.
  • Wound healing: St. John's wort extract exhibited a wound-healing activity whose mechanism of action is similar to that of Centella asiatica (TECA).

Poultry Specific Studies

TypePlant PartDosageSpecific useResultsRef
Chickensextract1330-667.9 mg/kg body weightantiviral, infectious bursal diseaseHad significant therapeutic efficacy and improvement immunologic functions for chickens infected experimentally with IBDV.R Shang et al., 2012
Otherextractwound healingincreased stimulation of fibroblast collagen production and the activation of fibroblast cells in polygonal shape, which plays a role in wound repair by closing damaged area. N Ozturk et al., 2007
Chickenspowder667.9 mg/kg body weight for 4 daysantiviral, infectious bursal diseaseEffectively treated infectious bursal disease in 20-day-old chickens infected with the virus. S Ruofeng et al., 2012
Otherextractwound healingWhen combined with silver sulfadiazine (SS) cream 1%, the extract of Hypericum perforatum had a synergistic effect on burn wound healing when applied topically to the area. It increased the amount of collagen and provided a meaningful anti-inflammatory effect. A Kurt et al., 2014