Gu-Sui-Bu

Rhizoma Drynariae

Benefits

Bone_strength

Gu-Sui-Bu (Rhizoma Drynariae) is one of the most frequently used traditional Chinese medicines for its antiosteoporosis activities related to improving bone strength and promoting bone fracture healing. These properties made it attractive to the poultry industry for improving bone strength of hens on low-calcium diets and broilers suffering from tibial dyschondroplasia.

Poultry Specific Studies

Type	Dosage	Specific use	Results	Ref
Chickens	125 mg/kg	additive	Improved oxidative stress and inflammatory response.	K Yue et al., 2023
Hens	2.0 g/kg	antiosteoporosis	Enhanced the activities of serum total antioxidant capacity and glutathione peroxidase. Increased femur and tibia bone mineral density. reduced the activities of serum alkaline phosphatase, tartrate resistant acid phosphatase, and the contents of osteocalcin. Improved microstructure of bone tissue. Significantly increased egg weight.	J Huang et al., 2020
Hens	500-2000 mg/kg	antiosteoporosis	Protected the bone tissue and prevented bone density from decreasing in the legs of hens on low-calcium diets.	J Huang et al., 2019
Chickens	20 mg/kg	tibial dyschondroplasia	Improved signs associated with tibial dyschondroplasia in chickens and allowed them to recover to normal activity.	W Yao et al., 2018

References

Huang, Shucheng, et al.. "Total Flavonoids of Rhizoma Drynariae Mitigates Aflatoxin B1-Induced Liver Toxicity in Chickens via Microbiota-Gut-Liver Axis Interaction Mechanisms" Antioxidants 12.4 (2023)
Lin, Luxi, et al.. "Total flavonoids of Rhizoma Drynariae protect hepatocytes against aflatoxin B1-induced oxidative stress and apoptosis in broiler chickens" Ecotoxicology and Environmental Safety 230 (2022)
Yue, Ke, et al. . "Novel Insights into Total Flavonoids of Rhizoma Drynariae against Meat Quality Deterioration Caused by Dietary Aflatoxin B1 Exposure in Chickens" Antioxidants 12.1 (2022)
Xu, Tingting, et al. "otal flavonoids of Rhizoma Drynariae ameliorate bone growth in experimentally induced tibial dyschondroplasia in chickens via regulation of OPG/RANKL axis" Frontiers in pharmacology 13 (2022)
He, Luqing, et al. . "Discussion on the Molecular Mechanism of Drynaria Total Flavonoids in Treating Hormonal Femoral Head Necrosis Based on Network Pharmacology" Frontiers in Medical Science Research 2.1 (2021)
Huang, J., et al. "Dietary supplementation of total flavonoids from Rhizoma Drynariae improves bone health in older caged laying hens" Poultry science 99.10 (2020)
Huang, Jie, Lei Zhang, and Zhongxin Zhou. "318 Total flavonoids from Rhizoma drynariae ameliorate low calcium-induced osteoporosis by regulating the bone metabolism in caged laying hens" Journal of Animal Science 97.Suppl 3 (2019)
Yao, Wangyuan, et al.. "Effect of total flavonoids of rhizoma drynariae on tibial dyschondroplasia by regulating BMP-2 and Runx2 expression in chickens" Frontiers in pharmacology 9 (2018)

Gu-Sui-Bu

Rhizoma Drynariae

Benefits

Poultry Specific Studies

References

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