| Type | Plant Part | Dosage | Specific use | Results | Ref |
|---|---|---|---|---|---|
| Chickens | 20-80 mg/kg body weight | anti-granuloma activity | ALA has notable anti-granuloma activity as compared to control in animal models of chronic inflammation. | MR Abdul-Ghani 2023 | |
| Chicks | 80 mg/kg of body weight intraperitoneally | neurological pain | Discovery of the optimal dosage for analgesic effects. | M Abdulghani et al 2022 | |
| Chickens | 500 mg/kg ALA added to diet. | heat stress | Improved ADG and FBW in heat-stressed birds. Increased expression of HSP90, PRDX1, GPX3, SOD2, OCLN, and MUC2 genes and higher concentrations of major VFAs (acetate, propionate, and butyrate). Improved the villus height and villus height to crypt depth ratio. The microbial diversity analysis revealed significant abundance of beneficial bacteria Lactobacillus and Peptostreptococcaceae in the cecum of the ALA group. | S Wasti et al., 2021 | |
| Chickens | 500 mg/kg ALA added to diet. | antioxidant, anti-inflammatory | Vitamin E and ALA especially when they were combined in the diet had positive effects on mitigating intestinal inflammation and improving nutrient transport beginning at 1 wk of age, which is likely critical in reducing the severity of wooden breast myopathy. | J Wang et al., 2021 | |
| Chickens | 500 mg/kg ALA added to diet. | heat stress, testicular injury | ALA may be beneficial for ameliorating decreased reproductive performance caused by heat stress | Y Xiong et al 2020 | |
| Chickens | 600 mg/kg ALA added to diet | Reproductive associated | Could improve lipid metabolism and reproductive performance of breeder hens. Significantly improved the eggshell thickness and strength. Improved the SOD activity and total antioxidant capacity level, along with a decreased MDA in ovarian tissue. The mRNA expressions of ESR1, ESR2, VTG2 and ApoB in the liver and FSHR in follicles were upregulated. Improved egg-laying rate. Elevated levels of HDL-C, ALB and estradiol (E2) of the serum. Reduced level of serum AST and TG. Increased the activity of hepatic lipase in liver | H Dai et al 2020 | |
| Chickens | 300 mg/kg ALA added to diet | antioxidant | May reduce the adverse effects of high stocking density-mediated stress by maintaining the antioxidant system and humoral immune system. | W Li et al., 2019 | |
| Chickens | 300 mg/kg ALA added to diet | ammonia toxicity | The addition of LA may reduce ammonia toxicity by maintaining the antioxidant system, xenobiotic metabolism, and metabolic pathways. | M Lu et al., 2017 | |
| Chicks | encapsulated form | 7.5-150 ppm | immunity, stress response, antibody titers | Decreased serum levels of the liver enzymes aspartate-aminotransferase (AST) and alanine-aminotransferase (ALT). Increased antibody response to Newcastle disease virus vaccine. Reduced concentration of cortisol. The encapsulated form of ALA was more effective than the powder form. | D Kim et al., 2015 |
| Chickens | 500 mg/kg ALA added to diet. | antioxidant | improved average feed intake and body weight gain. Significantly decreased abdominal fat yield. Improved hepatic total antioxidant capacity, the level of glutathione, the activities of total superoxide dismutase, catalase (CAT) and glutathione peroxidase. Decreased the activity of liver xanthine oxidase (XO). | Z Guo et al 2014 | |
| Chickens | 300 mg/kg ALA added to diet | antioxidant, aflatoxin toxicity | All of these negative effects were inhibited by treatment. | Y Li et al., 2014 |
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