Brand Names:
PGE, Prepidil Gel

Drug Type: Hormone


Prostaglandins are a group of lipids made at sites of tissue damage or infection that are involved in dealing with injury and illness. They control processes such as inflammation, blood flow, the formation of blood clots, and the induction of labor in humans. They are given in female poultry to help induce oviductal contractions.

However, this drug should only be administered by a veterinarian who should do so with extreme caution. This is because it can potentially cause the egg to rupture while inside the bird s reproductive tract.

When applied as a topical gel, it is less risky. There are four principal bioactive prostaglandins: prostaglandin (PG) E2 (PGE2), prostaglandin (PGI2) (this is also known as prostacyclin), prostaglandin D2 (PGD2) and prostaglandin F2α (PGF2α).
  • E2 is applied topically (0.02-0.1 mg/kg), and F2-alpha given IM, intracloacal once (0.02-0.1 mg/kg)

Gel and injectable
  • Egg rupture