Brand Names:
Trental, Pentoxil, Pentilin, Aotong


Drug Type: Antiinflammatory, Antioxidant, Alkaloid, Antiplatelet, Hemorrheologic_agent, Peripheral_vasodilator

Pentoxifylline

Pentoxifylline, also known as oxpentifylline, is a methylxanthine derivative used to improve blood flow. It is commonly indicated for use in humans with peripheral vascular disease. Pentoxifylline:
  • Increases red cell flexibility, enabling passage through damaged capillaries.
  • Decreases reperfusion-associated membrane injury and leukocyte adhesion to ischemic tissue.
  • Has been shown to significantly improve tissue survival in frostbitten animals, both alone and in combination with aloe vera cream (in rabbits) and aspirin (rats).
Pentoxifylline has been used in birds without adverse effects.

Pentoxifylline may help poultry suffering from conditions such as frostbite, atherosclerosis, and cardiovascular disease. It might also increase healing and strength in poultry recovering from tendon injuries or slipped tendon.
  • 15 mg/kg PO q8–12h for 2 to 6 weeks
tablet
  • Aspirin: The therapeutic efficacy of Pentoxifylline can be increased when used in combination with aspirin
  • Albendazole: The metabolism of Pentoxifylline can be decreased when combined with Albendazole.
  • Allopurinol: The serum concentration of Pentoxifylline can be increased when it is combined with Allopurinol.
  • Bismuth subsalicylate: The risk or severity of bleeding can be increased when Pentoxifylline is combined with Bismuth subsalicylate.
  • Carprofen:The risk or severity of bleeding can be increased when Carprofen is combined with Pentoxifylline.
  • Chloramphenicol: The risk or severity of bleeding can be increased when Pentoxifylline is combined with Chloramphenicol.
  • Diclofenac: The risk or severity of bleeding can be increased when Diclofenac is combined with Pentoxifylline.
  • Enalapril: Pentoxifylline may increase the hypotensive activities of Enalapril
  • Firocoxib:The risk or severity of bleeding can be increased when Firocoxib is combined with Pentoxifylline.
  • Flunixin:The risk or severity of bleeding can be increased when Flunixin is combined with Pentoxifylline.
  • Furazolidone:The risk or severity of bleeding and hemorrhage can be increased when Furazolidone is combined with Pentoxifylline.
  • Furosemide: Furosemide may increase the hypotensive activities of Pentoxifylline.
  • Ketoprofen: The risk or severity of bleeding can be increased when Ketoprofen is combined with Pentoxifylline.
  • Meclofenamic acid: The risk or severity of bleeding can be increased when Meclofenamic acid is combined with Pentoxifylline.
  • Meloxicam: The risk or severity of bleeding can be increased when Meloxicam is combined with Pentoxifylline
  • Robenacoxib:The risk or severity of bleeding can be increased when Robenacoxib is combined with Pentoxifylline.
  • Salicylic acid:The risk or severity of bleeding can be increased when Salicylic acid is combined with Pentoxifylline.
  • Vitamin E:Vitamin E may increase the antiplatelet activities of Pentoxifylline.

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