Brand Names:
Pitocin, Syntocinon

Drug Type: Hormone, Peptide


Oxytocin is a nonapeptide hypothalamic hormone stored in the posterior pituitary (in mammals). It is used to induce uterine contractions in hens, which makes it sometimes beneficial for certain cases of egg binding. Oxytocin is destroyed in the GI tract and, therefore, must be adminis­tered parenterally. After IV administration, uterine response occurs almost immediately. Following IM administration, the uterus responds generally within 3-5 minutes.

Caution: Oxytocin should not be used in female poultry if an egg is adhered to the oviduct, if the uterus is ruptured, or if the passage of the egg is blocked. Should be preceded by calcium administration for egg binding.

Storage/Stability: Oxytocin injection should be stored at temperatures of less than 25°C, but should not be frozen. Some manufacturers recommend storing the product under refrigeration (2-8°C), but some products have been demonstrated to be sta­ble for up to 5 years if stored at less than 26°C.
  • 0.5-10 U/kg IM
Available as an injectable solution
  • The drug can cause severe water intoxication due to its antidiuretic effect, leading to convulsions and death.
  • If given in high doses, or the bird is very sensitive to the drug, administering it can cause uterine hypertonicity, spasm, tetanic contraction, or rupture of the uterus.