Brand Names:
Reglan, Metozolv, Maxeran, Degan, Pramin, Pulin


Drug Type: Antiemetic

Metoclopramide

Metoclopramide is used for poultry with delayed crop emptying. The primary pharmacologic effects of metoclopramide are associated with the GI tract and the CNS. In the GI tract, metoclopramide stimulates motility of the upper GI without stimulating gastric, pancreatic or biliary secretions. Gastric emptying and intestinal transit times can be significantly reduced. There is little or no effect on colon motility. Additionally, metoclopramide will increase lower esophageal sphincter pressure and prevent or reduce gastroesophageal reflux.

Storage/Stability: Metoclopramide is photosensitive and must be stored in light resistant containers. All metoclopramide products should be stored at room tem­perature. Metoclopramide tablets should be kept in tight containers.

Caution: Metoclopramide is contraindicated in patients with GI hemorrhage, obstruction or perforation
  • 0.3-0.5 mg/kg PO, IM, IV q8-12h
injectable, tablets
  • Aspirin: Aspirin may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Albendazole: The metabolism of Metoclopramide can be decreased when combined with Albendazole.
  • Amikacin:Amikacin may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Carprofen: Carprofen may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Dexamethasone: The therapeutic efficacy of Metoclopramide can be decreased when used in combination with Dexamethasone.
  • Diazepam:The risk or severity of sedation can be increased when Diazepam is combined with Metoclopramide.
  • Doxycycline: Doxycycline may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Enalapril:The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Enalapril is combined with Metoclopramide.
  • Enrofloxacin: The metabolism of Metoclopramide can be decreased when combined with Enrofloxacin.
  • Folic acid: Folic acid may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Furosemide: Furosemide may increase the excretion rate of Metoclopramide which could result in a lower serum level and potentially a reduction in efficacy.
  • Griseofulvin: The metabolism of Metoclopramide can be increased when combined with Griseofulvin.
  • Ivermectin: The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ivermectin is combined with Metoclopramide.
  • Ketoprofen: Ketoprofen may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Meloxicam:Meloxicam may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Methylprednisolone:The therapeutic efficacy of Metoclopramide can be decreased when used in combination with Methylprednisolone.
  • Miconazole: The metabolism of Metoclopramide can be decreased when combined with Miconazole.
  • Niacin: The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Niacin is combined with Metoclopramide.
  • Piperazine:The metabolism of Piperazine can be decreased when combined with Metoclopramide.
  • Praziquantel:The metabolism of Metoclopramide can be decreased when combined with Praziquantel.
  • Prednisolone:The therapeutic efficacy of Metoclopramide can be decreased when used in combination with Prednisolone.
  • Pyridoxine:Pyridoxine may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Selenium:Metoclopramide may decrease the excretion rate of Selenium which could result in a higher serum level.
  • Tetracycline: Tetracycline may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Thiabendazole:The metabolism of Metoclopramide can be decreased when combined with Thiabendazole.

Popular Health Tools

Switch Animal