Brand Names:
Reglan, Metozolv, Maxeran, Degan, Pramin, Pulin


Drug Type: Antiemetic

Metoclopramide

Metoclopramide is a dopamine D2-receptor antagonist that is used as an antiemetic and gastroprokinetic agent in animals. It is often prescribed to help stimulate the motility of the gastrointestinal (GI) tract in chickens with delayed crop emptying issues that aren't caused by a blockage.

Caution: Metoclopramide should not be given to birds when reduced gastrointestinal motility is due to an obstruction. Don't administer to birds with gastrointestinal bleeding or perforation.

Storage/Stability: Metoclopramide is photosensitive and must be stored in light resistant containers. All metoclopramide products should be stored at room tem­perature. Metoclopramide tablets should be kept in tight containers.

Disclaimer: Use at your own risk. We assume no responsibility for the use of the drug, dosages given and for any misstatement, error, negligent, or otherwise.
  • 0.5-1 mg/kg PO IM q8-12h (J Mayer 2013)
  • (waterfowl) 2 mg/kg IM, IV q8-12h (B Speer 2016)
Available in tablets or syrup to be given orally or as an injectable solution to be given IM or IV.
  • May cause sedation
  • Aspirin: Aspirin may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Albendazole: The metabolism of Metoclopramide can be decreased when combined with Albendazole.
  • Amikacin:Amikacin may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Carprofen: Carprofen may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Dexamethasone: The therapeutic efficacy of Metoclopramide can be decreased when used in combination with Dexamethasone.
  • Diazepam:The risk or severity of sedation can be increased when Diazepam is combined with Metoclopramide.
  • Doxycycline: Doxycycline may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Enalapril:The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Enalapril is combined with Metoclopramide.
  • Enrofloxacin: The metabolism of Metoclopramide can be decreased when combined with Enrofloxacin.
  • Folic acid: Folic acid may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Furosemide: Furosemide may increase the excretion rate of Metoclopramide which could result in a lower serum level and potentially a reduction in efficacy.
  • Griseofulvin: The metabolism of Metoclopramide can be increased when combined with Griseofulvin.
  • Ivermectin:The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ivermectin is combined with Metoclopramide.
  • Ketoprofen: Ketoprofen may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Meloxicam:Meloxicam may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Methylprednisolone:The therapeutic efficacy of Metoclopramide can be decreased when used in combination with Methylprednisolone.
  • Miconazole: The metabolism of Metoclopramide can be decreased when combined with Miconazole.
  • Niacin: The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Niacin is combined with Metoclopramide.
  • Piperazine:The metabolism of Piperazine can be decreased when combined with Metoclopramide.
  • Praziquantel:The metabolism of Metoclopramide can be decreased when combined with Praziquantel.
  • Prednisolone:The therapeutic efficacy of Metoclopramide can be decreased when used in combination with Prednisolone.
  • Pyridoxine:Pyridoxine may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Selenium:Metoclopramide may decrease the excretion rate of Selenium which could result in a higher serum level.
  • Tetracycline: Tetracycline may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
  • Thiabendazole:The metabolism of Metoclopramide can be decreased when combined with Thiabendazole.

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