Brand Names:
Lupron


Drug Type: GnRH-agonist, Hormone

Leuprolide acetate

Leuprolide acetate (brand name Lupron®) is a synthetic gonadotropin-releasing hormone (GnRH) which is administered as a series of intramuscular (IM) injections. It is used 'off-label' for the treatment and prevention of a variety of reproductive tract-associated disorders in pet poultry.

Disclaimer: Use at your own risk. We assume no responsibility for the use of the drug, dosages given and for any misstatement, error, negligent, or otherwise.
  • 500-1000 mcg/kg q14d (J Mayer 2013)
Leuprolide acetate is given as an intramuscular (IM) injection
  • Reduced bone density, resulting in increased risk of fractures
  • Poor feather quality
  • Dexamethasone: The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Dexamethasone.
  • Enalapril: The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Enalapril.
  • Ivermectin: The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Ivermectin.
  • Naltrexone:The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Naltrexone.
  • Paclitaxel:The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Paclitaxel.
  • Phenytoin: The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Phenytoin.
  • Selenium: Leuprolide may decrease the excretion rate of Selenium which could result in a higher serum level.
  • Terbinafine:The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Terbinafine.
  • Trimethoprim: The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Trimethoprim.

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