Diltiazem is a calcium channel blocker used to treat atherosclerosis in chickens. It is an antihypertensive and vasodilating agent that relaxes the blood vessels so the heart does not have to pump as hard. It also increases the supply of blood and oxygen to the heart. It is also used to treat certain types of arrhythmias (abnormal heart rhythms).
In one study, chickens receiving this treatment showed a 30-40% decrease in lipid deposition of the aorta. (B Garcia Perez et al).
Overdose of this drug can be dangerous. There is no established toxic threshold for chickens but the dosage given below is considered the high range. Signs of toxicity include vomiting, decreased heart rate, low blood pressure, altered mental status, diarrhea and weakness.
