Brand Names:
Chloramex, Chloramphenicolum, Chlornitromycin, Chlorocid, Chlorocol


Drug Type: Antibiotic

Chloramphenicol

Chloramphenicol is a broad-spectrum antibiotic used to treat serious, life threatening bacterial infections in poultry. It is effective against a wide variety of microorganisms, however since oral absorption is erratic and the potential toxic side effects to the liver and kidneys, the drug is usually only used as a last resort.

In the United States, Chloramphenicol is not approved for use in poultry who are not kept as pets. It is given "off-label".

Caution: Chloramphenicol is known to cause bone marrow suppression and should be used with great caution in birds with any existing kidney or liver damage. Can also cause dangerous anemia.
  • Chloramphenicol palmitate (oral suspension): 25-50 mg/kg PO q8h
  • Chloramphenicol: 22 mg/kg IM, IV q3h (for ducks), 50 mg/kg IM q6-12h (other poultry)
injectable solution (100 mg/ml) or oral suspension
  • Kidney damage
  • Liver damage
  • Anemia
  • Amoxicillin:The metabolism of Amoxicillin can be decreased when combined with Chloramphenicol.
  • Clomipramine: The metabolism of Clomipramine can be decreased when combined with chloramphenicol.
  • Clotrimazole: The metabolism of Chloramphenicol can be decreased when combined with Clotrimazole.
  • Cyclosporine:The serum concentration of Cyclosporine can be increased when it is combined with Chloramphenicol.
  • Diazepam: The metabolism of Diazepam can be decreased when combined with Chloramphenicol.
  • Diclofenac: The metabolism of Diclofenac can be decreased when combined with Chloramphenicol.
  • Estradiol: The metabolism of Estradiol can be decreased when combined with Chloramphenicol.
  • Fluoxetine: The metabolism of Fluoxetine can be decreased when combined with Chloramphenicol.
  • Melatonin: The metabolism of Melatonin can be decreased when combined with Chloramphenicol.
  • Omeprazole: The metabolism of Omeprazole can be decreased when combined with Chloramphenicol.
  • Pentobarbital: The metabolism of Pentobarbital can be decreased when combined with Chloramphenicol.
  • Phenytoin: The metabolism of Phenytoin can be decreased when combined with Chloramphenicol.
  • Praziquantel: The metabolism of Praziquantel can be decreased when combined with Chloramphenicol.
  • Primidone: The metabolism of Primidone can be decreased when combined with Chloramphenicol.
  • Progesterone: The metabolism of Progesterone can be decreased when combined with Chloramphenicol.
  • Promazine: The metabolism of Promazine can be decreased when combined with Chloramphenicol.
  • Propofol: The metabolism of Propofol can be decreased when combined with Chloramphenicol.
  • Secobarbital: The metabolism of Secobarbital can be decreased when combined with Chloramphenicol.
  • Selegiline: The metabolism of Selegiline can be decreased when combined with Chloramphenicol.
  • Tamoxifen: The metabolism of Tamoxifen can be decreased when combined with Chloramphenicol.
  • Terbinafine: The metabolism of Terbinafine can be decreased when combined with Chloramphenicol.
  • Testosterone: The metabolism of Testosterone can be decreased when combined with Chloramphenicol.
  • Thiamylal: The metabolism of Thiamylal can be decreased when combined with Chloramphenicol.
  • Thiopental: he metabolism of Thiopental can be decreased when combined with Chloramphenicol.