Brand Names:
Keflex


Drug Type: Antibiotic

Cephalexin

Cephalexin is a first-generation cephalosporin antibiotic. It is used mainly for deep skin infections, such as bumblefoot. It is effective against most Gram-positive bacteria.

Note: Cephalosporins may disturb the normal intestinal microflora of poultry, particularly when administered orally and at high doses.

Egg Withdrawal Period: In the United States, Ireland, and the United Kingdom, cephalexin is approved for use in laying poultry producing eggs intended for human consumption when it's given in accordance with each product manufacturer s label directions; where it has a 0-day egg withdrawal period.

Toxicity: The oral median lethal dose of cephalexin in rats is >5000 mg/kg. The oral LD50 in a monkey is >1g/kg and the lowest dose causing a toxic effect in humans is 14 mg/kg.
  • 50-125 mg/kg IM, PO q6-12h
oral solution
  • Bacitracin: The risk or severity of nephrotoxicity can be increased when Cephalexin is combined with Bacitracin.
  • Carprofen: The risk or severity of nephrotoxicity can be increased when Cephalexin is combined with Carprofen.
  • Cefapirin:The risk or severity of nephrotoxicity can be increased when Cephalexin is combined with Cefapirin.
  • Cefpodoxime: The risk or severity of nephrotoxicity can be increased when Cephalexin is combined with Cefpodoxime.
  • Neomycin: The risk or severity of nephrotoxicity can be increased when Cephalexin is combined with Neomycin.
  • Ginkgo biloba: The metabolism of Cephalexin can be decreased when combined with Ginkgo biloba.