Brand Names:
Atropine sulfate

Drug Type: Anesthetic, Anticholinergic, Antitoxin


Atropine is a drug used to treat eye conditions, certain heart disorders, poisoning, and a few gastrointestinal conditions. Atropine is in a class of drugs known as anticholinergics. It works by blocking the actions of acetylcholine, a neurotransmitter that helps move electrical impulses among nerve cells. Atropine is administered during poisoning by pesticides and certain toxic plants (Azaleas (Rhododendron), mushrooms (False Morel Mushroom (Gyromitra), Mower s Mushroom (Gymnopilus), Common Toadstool Mushroom (Gymnopilus), and poisoning associated with bradycardia hyptension.

Caution. Excessive or inappropriate use can cause heart arrhythmias and death.
  • 0.01-0.02 mg/kg given IV or IM every 3-4 hours.
available as an injectable solution (0.5 mg/ml or 15 mg/ml) for IM or SC administration.
  • Cardiac arrhythmias
  • Gastrointestinal stasis
  • Increased heartrate
  • Restlessness
  • Abdominal swelling
  • Depression
  • Change in balance
  • Difficulty breathing
  • Lethargy
  • Belladonna (Donnatal, and others)
  • Benztropine (Cogentin)
  • Dimenhydrinate (Dramamine)
  • Methscopolamine (Pamine)
  • Scopolamine (Transderm-Scop)
  • Bronchodilators : such as ipratropium (Atrovent, Combivent) or tiotropium (Spiriva)
  • Digoxin (digitalis, Lanoxin)
  • Glycopyrrolate (Robinul)
  • Mepenzolate (Cantil)
  • Bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare)
  • Irritable bowel medicines such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine)