Drug Type: Antibiotic


Apramycin is an aminocyclitol antibiotic with a chemical structure very similar to that of the aminoglycosides but different enough to leave it unaffected by many aminoglycoside inactivating enzymes. Apramycin is active against Staphylococcus aureus, many gram-negative bacteria, and some mycoplasma strains.

Absorption: Apramycin is rapidly and well absorbed from intramuscular (IM) and subcutaneous (SC) routes of administration. It is poorly absorbed from oral administration in adult birds.
  • 0.5 g/L in drinking water QD
  • Nephrotoxicity (signs are polyuria and polydipsia) and ototoxicity are relatively common.
  • Aminoglycosides should be avoided or used with care in dehydrated patients.