Tetracycline is a broad-spectrum bacteriostatic agent that works by inhibiting protein synthesis. Other similar drugs include
Chlortetracycline,
Oxytetracycline, and
Doxycycline. Tetracyclines have activity against gram-positive and gram-negative bacteria, including some anaerobes. It is also active against
Chlamydia, Mycoplasmas, and some protozoa, and several rickettsiae. Specific bacteria within the tetracycline's activity range include
Escherichia coli, Klebsiella spp, Pasteurella spp, Salmonella spp, Staphylococcus spp, and
Streptococcus spp.
Tetracycline should only be administered orally, because it is poorly absorbed if administered via IM. It can be added to the flock's drinking water or feed. The half-life elimination for tetracycline in chickens is 2.8 hours.
Storage/Stability: Unless otherwise instructed by the manufacturer, tetracycline oral tablets and capsules should be stored in tight, light resistant containers at room temperature (15-30°C). The oral suspension should be stored at room temperature. Avoid freezing.