Brand Names:
Colcrys


Drug Type: Alkaloid

Colchicine

Colchicine is a drug most commonly used to treat avian gout, a metabolic disease where uric acid crystals deposit in joints creating pain. It is also used for the treatment of amyloidosis. This is because colchicine stimulates enzymes called collagenases, which break down collagen protein, inhibiting liver cells from making amyloid A.

Storage Recommendations
Colchicine tablets should be stored at room temperature and kept away from direct sunlight.
  • 0.04 mg/kg/day, BID, administered orally
Available in 0.6 mg tablets
  • May deplete the body of vitamin B-12 (cobalamin) in some cases.
  • Concurrent use of non-steroidal anti-inflammatory drugs (NSAIDs) may increase the negative bone marrow effects of the drug.