Brand Names:
Lipitor, Caduet


Atorvastatin

Atorvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke in humans.

There is limited research on its effects in birds, but preliminary findings suggest that some hypolipidemic effect can be seen in parrots. It may be beneficial for birds with lipid-accumulation disorders such as atherosclerosis and fatty liver disease.
  • 10 mg/kg PO q 12 h
  • Atropine:Atropine may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
  • Clindamycin:The risk or severity of adverse effects can be increased when Clindamycin is combined with Atorvastatin.
  • Dexamethasone: The metabolism of Atorvastatin can be decreased when combined with Dexamethasone.
  • Dexamethasone acetate: Dexamethasone acetate may increase the excretion rate of Atorvastatin which could result in a lower serum level and potentially a reduction in efficacy.
  • Diazepam: The metabolism of Atorvastatin can be decreased when combined with Diazepam.
  • Enalapril: The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Enalapril is combined with Atorvastatin.
  • Erythromycin: The serum concentration of Atorvastatin can be increased when it is combined with Erythromycin
  • Grapefruit: should not be given to birds on statins, as it may drastically increase plasma concentrations and side effects.
  • Ivermectin: The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ivermectin is combined with Atorvastatin.
  • Miconazole: The metabolism of Atorvastatin can be decreased when combined with Miconazole.
  • Nystatin: The excretion of Atorvastatin can be decreased when combined with Nystatin.
  • Praziquantel: The metabolism of Atorvastatin can be decreased when combined with Praziquantel.
  • Prednisolone phosphate: The metabolism of Atorvastatin can be increased when combined with Prednisolone phosphate.
  • Pyrimethamine: The metabolism of Atorvastatin can be decreased when combined with Pyrimethamine.
  • Sulfadiazine: The metabolism of Atorvastatin can be decreased when combined with Sulfadiazine.
  • Terbinafine:The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Terbinafine is combined with Atorvastatin.
  • Tetracycline: The metabolism of Atorvastatin can be decreased when combined with Tetracycline.