Paromomycin is a broad-spectrum aminoglycoside antibiotic which is used to treat intestinal parasitic infections involving protozoa. The in vitro and in vivo antibacterial action of paromomycin closely parallels that of neomycin.
Paromomycin has been used in the treatment of Cryptosporidium, Giardia and Histomonas meleagridis infections in birds.
Aminoglycoside antibiotics are toxic to the kidneys and therefore should be used with caution, especially in birds with renal disease.